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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1B
All Species:
19.09
Human Site:
S18
Identified Species:
42
UniProt:
P16401
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16401
NP_005313.1
226
22580
S18
T
P
A
P
V
E
K
S
P
A
K
K
K
A
T
Chimpanzee
Pan troglodytes
XP_527284
226
22578
S18
T
P
A
P
V
E
K
S
P
A
K
K
K
A
T
Rhesus Macaque
Macaca mulatta
P40286
208
22075
K19
A
V
P
A
V
M
E
K
P
L
T
K
K
R
G
Dog
Lupus familis
XP_545427
211
21163
S18
V
P
A
P
V
E
K
S
P
A
K
K
K
A
T
Cat
Felis silvestris
Mouse
Mus musculus
P43276
223
22558
S18
A
P
A
P
V
E
K
S
P
A
K
K
K
T
T
Rat
Rattus norvegicus
P15865
219
21969
T18
A
P
A
P
A
E
K
T
P
I
K
K
K
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
T18
P
S
A
P
A
E
K
T
P
T
K
K
R
A
K
Chicken
Gallus gallus
P08284
219
22026
K18
D
A
P
A
P
G
A
K
A
A
A
K
K
P
K
Frog
Xenopus laevis
P06892
210
21355
K21
A
E
P
A
A
K
K
K
K
Q
Q
P
K
K
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
V25
A
T
V
E
K
K
V
V
Q
K
K
A
S
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
A28
A
A
E
M
V
A
T
A
I
T
E
L
K
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
52.2
89.3
N.A.
90.7
82.3
N.A.
76.1
72.5
61
N.A.
N.A.
41
N.A.
N.A.
41.5
Protein Similarity:
100
99.5
63.7
91.1
N.A.
92.4
85.8
N.A.
82.7
76.1
68.5
N.A.
N.A.
50.7
N.A.
N.A.
50.8
P-Site Identity:
100
100
26.6
93.3
N.A.
86.6
66.6
N.A.
53.3
20
13.3
N.A.
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
33.3
93.3
N.A.
86.6
73.3
N.A.
66.6
20
26.6
N.A.
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
19
55
28
28
10
10
10
10
46
10
10
0
46
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
10
10
10
0
55
10
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
19
64
28
10
10
64
73
82
10
19
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% L
% Met:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
46
28
55
10
0
0
0
64
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
19
% R
% Ser:
0
10
0
0
0
0
0
37
0
0
0
0
10
0
10
% S
% Thr:
19
10
0
0
0
0
10
19
0
19
10
0
0
10
37
% T
% Val:
10
10
10
0
55
0
10
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _